Trulicity For Weight Loss: Uses, Dosages, Side Effects & More
Medically reviewed by Christiana George Updated Date: May 13, 2026
Weight loss is an obsession of many people these days. Around half of the US population tries to lose weight each year. Maintaining a normal weight is important because obesity increases the risk of many health conditions, including heart attacks, strokes, and type 2 diabetes. To try to lose weight, some people opt to try various weight loss medications. And Trulicity for weight loss is one of these.
Trulicity (dulaglutide) is an FDA-approved injectable medication to treat type 2 diabetes. It regulates blood sugar levels when used in conjunction with diet and exercise. The amount of trulicity one should use for weight loss depends on the dosage of drugs the individual is taking.
Although Trulicity is not a weight loss medication, it can help some people lose weight. Continue reading to learn more about Trulicity and how it may be able to help you lose weight.
Does Trulicity Work for Weight Loss?
Trulicity contains glucagon-like peptide 1 (GLP-1 ) agonists. It is an incretin hormone that regulates blood sugar levels. Your body releases incretin naturally after you eat. It stimulates the release of insulin from the pancreas (an organ next to the liver). This prevents blood sugar (glucose) levels from getting too high. Incretins help your body in digestion and provide a feeling of satiety after eating.
GLP-1 releases insulin by binding to GLP-1 receptors (chemical binding sites) in the pancreas. Trulicity works by mimicking the actions of GLP-1. It activates (turns on) the GLP-1 receptor, which signals the pancreas to release more insulin and less glucagon. The result is a decrease in blood sugar levels.
Is Trulicity Approved For Weight Loss?
Trulicity (an injectable medication ) is not FDA-approved for treating type 2 diabetes. But weight loss may be an additional benefit for people taking Trulicity to help manage their type 2 diabetes. It is necessary to follow a healthy eating regimen and exercise along with Trulicity to receive the maximum benefits from this medication.
How Does Trulicity Lead To Weight Loss?
Trulicity can help with weight loss for people with type 2 diabetes. Trulicity generally regulates blood sugar levels in patients with type 2 diabetes. This is because our bodies have a hormone called incretin. When we eat food, our stomach releases the incretin hormone. It helps regulate blood sugar levels by assisting cells in absorbing maximum glucose to convert into energy forms.
Type 2 diabetes patients are deficient in this hormone. The use of Trulicity, in this case, is to regulate blood sugar levels.
The actual mechanism of action of Trulicity is:
Trulicity and the incretin hormone act on the body and reduce gut motility. This combination slows down the process of emptying the gastrointestinal tract. As a result, the food remains in the GI tract longer. This prolongation of food keeps us full for a long time. This feeling of fullness suppresses our feeling of hunger, and this decrease in appetite causes a person to eat less. That’s how trulicity helps with weight loss.
How Much Weight Do You Lose With Trulicity?
Several studies found that the rate of weight loss depends on the dose of Trulicity you take. A research study concluded that after about 9 months of treatment, people taking 4.5 mg of Trulicity experienced more weight loss (about 10 pounds) than people taking 1.5 mg of Trulicity, who lost just under 7 pounds.
People lost an average of two to six pounds while taking Trulicity for weight loss.
However, between 15 and 30% of people gained weight. One of the ways Trulicity works is by helping you feel full after a meal. Among the people most likely to lose weight are those with a higher starting weight and a longer duration of GI side effects.
What Is the Dose of Trulicity for Weight Loss?
Trulicity’s maker, Eli Lilly, reported a 36-week clinical study in people with a BMI (body mass index) either greater than or less than 33.2. During the study, researchers gave different Trulicity doses (0.75 mg, 1.5 mg, 3.0 mg, or 4.5mg) to people.
The study showed the differential outcomes of Trulicity doses for weight loss. People with higher starting BMIs who took higher doses of Trulicity had the greatest weight loss, measured in pounds lost from baseline. The average weight loss for the highest dose of Trulicity (4.5 mg) was 10.1 lbs.
| Trulicity Dosage | Potential Weight Loss |
| 0.75 mg | 4.5 pounds |
| 1.5 mg | 6-7 pounds |
| 3 mg | 8.5 pounds |
| 4.5 mg | 10.1 pounds |
How Much Trulicity Is Safe to Consume?
The recommended dose of Trulicity is 1.5 mg once a week. For people who are most susceptible to high doses, 0.75 mg once weekly may be considered as the starting dose. For added glycemic control, the 1.5 mg dose can be increased to 3 mg per week after at least 4 weeks on the lower dose.
How To Use Trulicity For Weight Loss?
Specific investigations discovered that the amount of weight loss and improvement in blood glucose levels was portion related.
This implies that individuals on Trulicity 4.5 mg had more weight reduction (around 10 lbs) than individuals on Trulicity 1.5 mg (somewhat less than 7 lbs) after around nine months of treatment.
Higher doses of Trulicity additionally brought down blood glucose more than lower dosages. Trulicity comes as a single-portion infusion pen. There are four pen doses available:
- 0.75 mg
- 1.5 mg
- 3 mg
- 4.5 mg
Always inject the medicine subcutaneously (under the skin) in the following regions:
- Upper arm
- Thigh
- Midsection
You’ll have to inject Trulicity once each week. You should change your injection site weekly to allow the previous injection site to heal.
For people who are prone to weight loss medication. The initial dose of Trulicity is 0.5 mg once a week. If blood sugars remain high for the subsequent seven days, the dose can be raised to 1.5 mg per week.
If blood sugar values remain high on 1.5 mg per week, your physician may raise your dose to 3 mg per week, and if your blood sugars are still high, they can raise your dose to 4.5 mg per week. This is the highest dose available.
How To Increase Trulicity Benefits?
Trulicity is a once-a-week diabetes medication. It reduces the risk of cardiovascular problems. It is not safe to take Trulicity for weight loss more frequently than once per week.
You can use Trulicity at any time of the day, regardless of the timing of your meals. Try not to mix up Trulicity with different medications like insulin. Each pen contains a single dose of a drug and is for one-time use only. Keep in mind the following measures to increase the benefits of Trulicity.
- Keep your Trulicity in the refrigerator. Take it out shortly before your injection to allow it to come to room temperature prior to injection.
- Avoid eating grapefruit or drinking grapefruit juice with Trulicity.
- Avoid or really limit your caffeine intake.
- Avoid the use of alcohol while on Trulicity as it can cause stomach upset, loose stools, and vomiting.
Weight loss with any medication is possible. Your physician can give you additional advice, such as dietary guidance and exercise recommendations.
Trulicity Alternatives For Weight Loss
With the advancement of science and invention, new medications are continuously being developed and becoming available on the market. I have listed many alternatives to Trulicity that are available. These alternatives work exactly like Trulicity. Have a look at them!
Trulicity Vs Ozempic For Weight Loss: Is Ozempic A Good Alternative To Trulicity?
Ozempic is an injectable prescription drug manufactured by Novo Nordisk. It is FDA-approved for weight loss. Just like Trulicity, it is injected subcutaneously. It is available in doses of 0.25mg, 0.5mg, and 1mg. Ozempic is also taken once a week and it is also used to treat type 2 diabetes.
| Dosage | Potential Weight Loss |
| 0.25 mg | 6.2 lbs |
| 0.5 mg | 9.3 lbs |
| 1 mg | 12.8 lbs |
Wegovy Vs Trulicity For Weight Loss: Is Wegovy A Good Alternative To Trulicity?
Wegovy is an injectable medication that works exactly like Trulicity. The FDA has approved Wegovy for weight loss. However, the only contradiction is that the salt in wegovy has higher potency than trulicity. It is available in doses of 0.25mg, 0.5mg, and 1mg. Just like Trulicity, Wegovy is also taken once a week, and it is also used to treat type 2 diabetes.
| Dosage | Potential Weight Loss |
| 0.25 mg | ~ 8 lbs |
| 0.5 mg | ~ 15 lbs |
| 1 mg | ~ 17 lbs |
| 1.7 mg | ~ 19 lbs |
| 2.4 mg | 20-30 lbs |
Trulicity vs Victoza for Weight Loss: Is Victoza a Good Alternative to Trulicity?
Victoza is also manufactured by Novo Nordisk. It contains liraglutide as an active ingredient. In contrast with Trulicity, it is available in doses of 0.6 mg, 1.2 mg, and 1.8 mg. Victoza should be taken once daily. Victoza helps regulate blood sugar levels in people with type 2 diabetes.
| Dosage | Potential Weight Loss |
| 0.6 mg | 4 lbs |
| 1.2 mg | 5.9 lbs |
| 1.8 mg | 7.3 lbs |
Trulicity Vs Metformin For Weight Loss: Is Metformin A Good Alternative To Trulicity?
Like Trulicity, metformin is a diabetes medication. It helps control blood sugar levels in people with type 2 diabetes. The amount of weight loss that occurs as a result of taking metformin is generally fairly small. This medication can be taken once or twice a day. Your doctor can prescribe both drugs if you need to lower your blood sugar level.
| Dosage | Potential Weight Loss |
| 500 mg | ~ 2-3 lb |
| 750 mg | ~4 lbs |
| 850 mg | 5.9 lb |
| 1000 mg | ~ 8 lbs |
| 2000 mg | ~15 lbs |
Trulicity Vs Liraglutide For Weight Loss: Is Liraglutide (Saxenda) A Good Alternative To Trulicity?
Saxenda is an injectable medication. Liraglutide helps people lose weight by suppressing your appetite. Its chemical structure is 97% similar to trulicity. Both these medications release Glucagon-like peptide-1 (GLP-1), a hormone in response to food intake to produce feelings of fullness and satiety. Take one dose of liraglutide daily.
| Dosage | Potential Weight Loss |
| 1.2 mg | 16 lbs |
| 1.8 mg | 17.1 lbs |
| 2.4 mg | 19 lbs |
| 3 mg | 17.6 lbs |
Trulicity Vs Mounjaro For Weight Loss: Is Mounjaro A Good Alternative To Trulicity?
Just like Trulicity, Monjaro is an injectable prescription drug used along with diet and exercise to improve blood sugar (glucose) levels in adults with type 2 diabetes mellitus. Although, it is not a weight-loss drug, many people experience weight loss with continuous use. It is available in doses including 2.5 mg, 5 mg, and 7.5 mg.
| Dosage | Potential Weight Loss |
| 2.5 mg | ~8 lbs |
| 5 mg | ~12 lbs |
| 7.5 mg | 16 lbs |
| 15 mg | 25 lbs |
Some Other Side Effects Of Trulicity
Trulicity helps lower blood sugar levels in patients with type 2 diabetes. Sometimes people take a higher dose of Trulicity than required by the body. This can cause blood sugar levels to drop too much. This also causes an unhealthy rate of weight loss.
So, we recommend you start Trulicity at a low dose of 0.75 mg or 1.5mg. If no noticeable side effects occur, you can increase your dose to the amount required at that time.
Your physician will determine the proper starting dose for you, and will increase your dose if and when it becomes necessary.
The most well-known side effects of Trulicity are gastrointestinal (GI) side effects. Individuals typically experience GI side effects within a few days of using Trulicity. Examples of symptoms include.
- Feeling sick to one’s stomach
- Loose bowels
- Vomiting
A rare but serious incidental effect is low blood glucose (hypoglycemia). Hypoglycemia is characterized by blood glucose levels under 70 mg/dL. A few signs and symptoms of hypoglycemia include:
- Unsteadiness
- Rapid pulse
- Sweating
- Hunger
- Feeling uneasy
- Drowsiness
- Feeling feeble
- Shivering
Check your blood glucose immediately if you experience any of these side effects. Adhere to your physician’s instructions for treating hypoglycemia, (for example, the “15-15 Rule”) and inform your doctor quickly.
FAQs
What Is Dulaglutide Used For?
It is an injectable medication for people with diabetes. It is necessary to accompany dulaglutide use with a healthy eating and exercise routine for maximum benefits. Dulaglutide controls blood sugar levels in patients with type 2 diabetes (a state in which the body is unable to regulate blood sugar levels appropriately).
Can I Use Trulicity With Insulin?
Yes, you can use them together. You just need to reduce the quantity of insulin. Trulicity and insulin jointly increase the regulation of blood sugar levels. Hence, more glucose is converted into energy. But only people with type 2 diabetes can use trulicity.
Does Dulaglutide Cause Weight Loss?
Although it is not a weight loss medication specifically, it just suppresses your appetite. A person taking trulicity can lose an average of 3-4 pounds. However, some people have experienced 15-30% weight gain.
Can Non-diabetic Patients Take Trulicity for Weight Loss?
People who don’t have diabetes should not take trulicity just for the sake of weight loss. Weight loss by trulicity is a concept that depends on your overall metabolic rate and food intake.
What Foods Should You Avoid While Taking Trulicity?
Avoid eating fatty foods and high-sugar foods. They slow your metabolic rate and are difficult to digest. Most commonly, these foods cause nausea when taken along with trulicity.
Bottom Line
Trulicity for weight loss is a GLP-1 agonist that treats type 2 diabetes when used with diet and exercise. It is also helpful in treating heart problems in people with type 2 diabetes, existing coronary disease, or risk factors for coronary disease.
While Trulicity isn’t FDA-approved for weight loss, it helps assist individuals to shed a few pounds, particularly at a dose of 4.5 mg each week. The most widely recognized side effects include stomach upset, nausea, and heaving.
Individuals without type 2 diabetes should not use Trulicity. Other GLP-1 agonists like Wegovy and Saxenda are FDA-approved for weight loss at times. Speak with your physician if you’re keen on using a GLP-1 agonist for weight loss.
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Is Kombucha Acidic? Is It Good For Acid Reflux?
The combination is pretty weird! Black tea, yeast, and sugar, and you got kombucha.
Kombucha lovers say this fermented tea is great for boosting energy, helping in digestion, and removing toxins from your body. But others say they have issues with the versatile taste-sometimes sweet or sometimes tangy.
You must be wondering about the diversity. And trying to figure out if kombucha is acidic or not?
Kombucha is acidic with the pH range between 2.5 to 4.2. When you ferment the kombucha tea, it produces less than 1% acetic acid which has a pH level of 3.0-3.5. This acid is responsible for the tangy nature of kombucha. Surprisingly, moderate amount kombucha is good for reducing acid reflux too.
However, the actual pH level is dependent on the tea types, tea-sugar-yeast ratio, brew time, room temperature, and the length of fermentation.
Keep reading to learn more about the acidic nature of kombucha and its relationship with acid reflux.
Kombucha – Acidic Or Alkaline?
In one line, kombucha is acidic, not alkaline. Let me explain why!
Black tea, green tea, white tea, or oolong tea are used for making kombucha. However, black tea for its oxidized leaves nature is mostly preferable for making a perfect kombucha.
And the pH of black tea is 4.9-5.5 which is a good range to grow yeast perfectly.
With time, the yeast of SCOBY (symbiotic culture of bacteria and yeast) starts eating the sugar content of the kombucha. That results in producing ethanol and it gradually turns acidic.
What about green tea or white tea kombucha? Well, they are neutral or basic, but with the fermenting process over time, the alkaline nature will vanish and turn into acidic for the yeast.
pH of Kombucha
The pH of kombucha is directly related to the fermentation time. However, tea types and ratios also take part in the pH level of kombucha.
And the pH value defines whether kombucha will taste sweet or tart. The pH like 3.5 ensures it will taste sweet. The lower pH like 2.5 makes the kombucha tart.
| Type | pH |
| Homemade Kombucha | 2.5 – 3.0 |
| Black Tea Kombucha | 5-5.5 |
| Green Tea Kombucha | 3.05 |
| White Tea Kombucha | 2.5 – 3.5 |
| Kombucha Rosella Tea | 2.86 |
| GT’s Kombucha | 2.5 – 3.5 |
| Kombucha brewed | 2.5 – 4.2 |
| Humm Kombucha | 3.0 |
| Sweet Kombucha | 3.5 |
3 Ways: How To Raise The pH Of Kombucha?
When you ferment kombucha, acetic and gluconic acid start producing by the fermenting bacteria. That results in a lower pH level and makes the taste too tart.
Also, lower pH means the kombucha is highly acidic which is not good for you especially if you are struggling with acid reflux.
Besides, when the taste is too tart, you may want to make it a little sweet. To make kombucha sweet, you have to increase the pH level. Here 3 ways to increase the pH of Kombucha –
1. Less Ferment Time
In general, the fermenting process takes from 7 days to 30 days. The more you ferment, the kombucha will be more acidic and vice versa. To make it less acidic, you can brew after the first fermentation which may take 6 to 10 days.
2. Keep It in Room Temperature
Kombucha brewing temperature affects the pH value directly. More than 85°F speeds up the culturing, which will result in lower pH.
To increase the pH level, you should keep the kombucha vessel at room temperature in between 68-78°F.
3. Maintain The Tea Leaf Ratio
Using more tea leaves can cause lower pH for the tea leaves’ oxidation nature over time. For each one-gallon batch, keep the ratio 6:1 for the tea leaves.
You can use 6 teaspoons of loose tea or 6 tea bags for each batch. So, keep the ratio perfect to get a higher pH kombucha.
How Acidic Is Kombucha For The Body?
Kombucha is acidic, but after drinking, it alkalizes the body. It’s because when you make kombucha using black or green tea, there will be several essential minerals such as manganese, potassium, copper, iron, fluid iron, etc.
The pH of our blood is 7.4 regarded as neutral. When these minerals of kombucha enter our bloodstream, that creates an alkalizing effect and results in a neutral state of our body.
Who Should Not Drink Kombucha? Are You in the 4 Categories?
Kombucha is considered safe and healthy to promote a healthy and smooth digestive system, boost energy and remove body toxins.
However, you are prohibited to drink kombucha under the following health conditions-
1. People With A Weak Immune System
As bacteria and yeast take an active part in kombucha, that may cause infection for people with weak immune systems.
2. Diabetics Patient
Kombucha contains a good amount of sugar. So it may increase blood sugar levels. Also, alcohol production during fermentation can cause complications for diabetic patients.
3. Pregnant, Breastfeeding Women And Kids
For the alcohol and caffeine, pregnant and breastfeeding women should avoid kombucha. Similarly, the bacteria and yeast might be harmful to the developing baby.
Additionally, kids should not drink kombucha. The carbonate effect of kombucha will cause stomach upset.
4. People With Stomach Ulcers
If you have stomach ulcers, kombucha may make it worse. The bacteria and acidic nature of kombucha can potentially aggravate stomach ulcers.
Is Kombucha Good For Acid Reflux?
Acid reflux occurs when you eat or drink high acidic or high-fat content food and drinks. if you have a lower esophageal sphincter (LES), your stomach content leaks up back. That causes acid reflux.
Now the question is what about kombucha? Is it good for acid reflux or promotes acid reflux?
The nature of kombucha is acidic, so you may think it’s not good for acid reflux. But the truth is kombucha is good for people who are suffering from acid reflux.
Kombucha contains lactic acid which has probiotic properties. That can kill harmful bacteria as well as promote smooth digestion. So far, lactic acid is beneficial to reduce the chances of acid reflux.
The tea drink is a great source of vitamin B. vitamin B can improve your gut health by controlling the production of stomach acid.
Several essential minerals of kombucha neutralize the acidic properties and make it alkalizing for your body.
For these activities, kombucha is good for acid reflux. However, you should be concerned about your daily intake. You can drink around 4 ounces per day to avoid health complications. Also, avoid adding high sugar content to it to get the best result.
Is Kombucha Bad For Acid Reflux?
Drinking too much kombucha causes acid reflux. The recommended level is 4 ounces per day for 1 to 3 times.
However, kombucha will be bad for acid reflux under certain health conditions.
First of all, if you already have the symptoms of acid reflux, drinking too much kombucha may make it worse.
Kombucha contains a decent amount of caffeine and alcohol. Both can increase the acid production in your stomach and irritate your digestion which causes heartburn too.
A lengthy fermentation process makes kombucha carbonated. And the carbonated nature feels your stomach fuller and pressurizes your lower esophageal sphincter. As a result, the acid flow starts moving back into the esophagus which leads to acid reflux directly.
In addition, the acetic acid of kombucha may also be responsible for acid reflux or GERD by disturbing your regular digestive system.
Various Forms Of Kombucha And Its Acidity
In the USA, around 14. 1 percent of adults drink kombucha in various forms such as kombucha tea, raw or hard kombucha for several purposes. The pH level and acidity are also different for each type.
Is Kombucha Tea Alkaline Or Acidic?
Kombucha tea is acidic with a pH range of 2.5 to 3.5. However, using tea bags instead of tea leaves makes kombucha tea more acidic for rapid oxidation.
The type of tea affects the acidity of kombucha. If you use pure black tea, it will make kombucha too acidic as black teas are already acidic in nature.
pH wise oolong tea kombucha will be almost the same as the black tea version. Though green tea and white tea kombucha seem alkaline for their higher pH values. But during the fermentation process, the basic nature will be removed.
Whether you use either green or white tea, the resulting kombucha tea will be acidic with a pH below 4.6. However, adding fruits or herbs can reduce the acidity of kombucha tea.
Related Post: Is Tea Acidic? 5 Non-acidic Alkaline Tea for You!
Is Hard Kombucha Acidic?
Hard kombucha is more acidic than kombucha tea. It’s the boozier version of the regular or raw kombucha. As hard kombucha fermented at 28°C/82.4°F or higher for 5 to 14 days, it will taste tangy and slightly vinegary.
Warm temperatures and lengthy fermentation, increases the ABV (alcohol by volume) and decreases the pH level to around 2.5.
Is Raw Kombucha Acidic?
Raw kombucha is not pasteurized though it’s acidic with a pH of less than 4.6. Mostly, the pH level of raw kombucha is 2.5-3.5. During the fermentation period, the yeast starts feeding the sugar content and creates a suitable environment to grow gradually. This process enhances the pH level of the raw kombucha drink.
Fun fact: Do you know when and where the kombucha tea originated? In 220 BC, kombucha originated in China. Then it reaches Russia, USA, Germany and all over the world.
FAQs
Is Kombucha Highly Acidic?
Yes, kombucha is highly acidic. The pH level of kombucha can range from 2.5 to 3.5, making it acidic. However, the acidity of kombucha is not harmful and can actually be beneficial for your health.
Is Kombucha Good For An Acidic Stomach?
Yes, kombucha can be good for an acidic stomach. This is because kombucha is rich in probiotics, which can help to balance the levels of acid in the stomach. At the same time, it can improve digestion, reduce inflammation and promote a healthy immune system.
Is Kombucha Acidic For Teeth?
Drinking too much kombucha is acidic for teeth. The acidity and sugar in kombucha can lead to tooth decay and other dental problems damaging tooth enamel. This is why it’s important to drink kombucha in moderation and to brush your teeth after drinking it.
Is Kombucha Bad For Ulcers?
Mostly, kombucha can be bad for people with ulcers. The fermented tea drink contains acetic acid, which can irritate the already inflamed lining of the stomach and intestines. In addition, the probiotics in kombucha can also increase gastric acid production, further exacerbating the symptoms of ulcers.
Is Kombucha Part Of An Alkaline Diet?
Kombucha is part of an alkaline diet. The fermentation process of kombucha results in a slightly acidic beverage with a pH between 2.5 and 3.5. However, after the drink is consumed, it leaves behind alkaline ash in the body that helps to neutralize acidity.
Does Kombucha Make Your Body Acidic or Alkaline?
Kombucha is acidic but it makes your body alkalize when it enters the bloodstream. The acidic nature neutralizes by the neutral pH of the blood and acts like alkalize to your body.
Bottom Line
Now it’s time to wrap up the discussion on: “is kombucha acidic”. Hopefully, you can understand the acidic nature and its role in acid reflux.
In summary, kombucha is acidic but a moderate amount is good for acid reflux. Also, the probiotics of kombucha are beneficial for sound digestion, weight loss, preventing GERDs as well as keeping your skin healthy.
Eat healthy, live healthy.
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