Trulicity for weight loss: Side effects, dosages, uses, and more

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Christiana George
Christiana George
Welcome to The Tart Tart, my not-so-tart take on food, writing, and photography. I decided to start up this sucker after repeated nagging from Chris, my fiance, who cannot understand why the sight of a farmer’s market would send me into ecstatic convulsions (okay, total overstatement. I can be quite the histrionic at times). With that said, my interests, though chiefly in food, also span fashion, design, literature, and photography. So don’t mind the seemingly non sequitur odds and ends I toss in posts at times.

Weight loss is the recent obsession of many people these days. Around half of the US, population tries to lose weight each year.

Apart from having an obsession, it is necessary to have an average weight as obesity causes many health risks like heart attack, stroke, or type 2 diabetes. However, weight loss obsession has come a long way, and now people opt for various methods of losing weight.

An FDA-approved injectable medication called trulicity, Dulaglutide. It helps treat type 2 diabetes when used cooperatively with diet and exercise. The Trulicity for weight loss ratio depends on the dosage of drugs the individual uses. Trulicity is approved to minimize heart disease in people with type 2 diabetes.

Trulicity can help some people lose weight. This article will discuss trulicity and how it can help people lose weight.

How does trulicity lead to weight loss?

The FDA has not specifically approved Trulicity or GLP-1 (glucagon-like peptide-1 receptors) as a weight-loss aid. However, it can help with weight loss for people with type 2 diabetes. In addition, people following diet and exercise along with trulicity injections have shown positive outcomes in losing weight.

Trulicity generally regulates blood sugar levels in patients with type 2 diabetes. This is because our bodies have a hormone called incretin. When we eat food, our stomach releases the incretin hormone. It helps regulate blood sugar levels by assisting cells in absorbing maximum glucose to convert into energy forms.

Type 2 diabetes patients are deficient in this hormone. The use of trulicity, in this case, is to regulate blood sugar levels.

The actual mechanism of action of trulicity is:

Trulicity and the incretin hormone act on the body and reduce gut motility. This combination slows down the process of emptying the gastrointestinal tract. As a result, the food remains in the GI tract for longer. This prolongation of food keeps us full for a long time. This feeling of fullness suppresses our hunger. That’s how trulicity helps with weight loss.

How to increase trulicity benefits?

Trulicity is a once-a-week diabetes drug likewise endorsed to bring down cardiovascular problems. It is not given more frequently than at regular intervals.

It is typically given at any time of day, regardless of meals. Try not to mix up trulicity with different medications like insulin. Each pen is named after the portion and is for single use.

  • Put away the trulicity in the cooler. Take it out for a brief timeframe preceding the infusion to permit it to come to room temperature and be a less acute infusion.
  •  Avoid using grapefruit or grapefruit juice with trulicity.
  • Caffeine consumption in typical amounts is additionally protected.
  • While alcohol isn’t contraindicated with Trulicity, it can cause stomach upset, looseness of the bowels, or vomiting. Consume alcohol capably and in limited amounts.

Weight loss with any medication is possible, along with diet and physical exercise. Your medical care supplier can guide you to different assets like your eating regimen and workout schedule.

How to use trulicity for weight loss?

Specific investigations discovered that the level of weight loss and improvement in blood glucose levels was portion related.

This implies that individuals on Trulicity 4.5 mg had more weight reduction (around 10 lbs) than individuals on Trulicity 1.5 mg (somewhat less than 7 lbs) after around nine months of treatment.

Higher portions of Trulicity additionally brought down blood glucose more than lower dosages. Trulicity comes as a single-portion infusion pen. There are four pen doses accessible:

  • 0.75 mg
  • 1.5 mg
  • 3 mg
  • 4.5 mg

Always infuse the medicine subcutaneously (under the skin) in the accompanying regions:

  • Upper arm
  • Thigh
  • Midsection

You’ll have to infuse Trulicity once each week. You should use an alternate infusion site weekly to allow the region to recuperate.

How to Use Trulicity

Trulicity dosage

The beginning portion of Trulicity is 0.75 mg once a week. The following seven days. If the blood glucose is still high, you can raise it to 1.5 mg.

In the wake of arriving at the 1.5 mg portion. If your blood glucose is as yet uncontrolled, raise your portion by 1.5 mg like clockwork. The most extreme portion is 4.5 mg once each week.

Other weight loss medications for diabetes patients

Recall that Trulicity isn’t FDA-supported for individuals without Type 2 diabetes, and we don’t have data about Trulicity in individuals without diabetes. However, other GLP-1 agonists are FDA-supported for weight reduction.

Presently, the main GLP-1 agonists supported for weight reduction are Wegovy (semaglutide) and Saxenda (liraglutide).

Semaglutide is additionally accessible as Ozempic and Rybelsus, and liraglutide is accessible as Victoza. However, both are only FDA-approved for use in people with Type 2 diabetes.

Wegovy and Saxenda work in a way to advance weight reduction in individuals with a body mass index (BMI) of something like 30 kg/m2.

People with a BMI of less than 27 kg/m2 use these medications for weight-related medical conditions such as hypertension, Type 2 diabetes, or high cholesterol.

In the AWARD 6 preliminary, Victoza (liraglutide) contradicted Trulicity. This investigation discovered that the weight loss related to Victoza was altogether better compared to that related to Trulicity.

We would expect this because with Saxenda, another notable effect of liraglutide, is that the company promoted and endorsed it for weight loss.

Metformin, a solution diabetes drug in the sulfonylureas class, is ordinarily a first-line treatment for type 2 diabetics and has likewise been connected to weight reduction, though they do not endorse it for this purpose.

The AWARD 3 preliminary showed comparable rates of weight reduction among Trulicity and metformin-treated patients.

Metformin is conventional and extremely savvy. It is also an oral prescription, while other GLP-1 receptor agonists are practically all injectable medications.

Side effects from trulicity

The most well-known risks of Trulicity are gastrointestinal (GI) aftereffects. Individuals typically experience GI side effects within a few days of using Trulicity, for example.

  • Sickness
  • Loose bowels
  • Vomiting

A more uncommon yet more serious incidental effect is low blood glucose (hypoglycemia). Hypoglycemia is regularly characterized as blood glucose levels under 70 mg/dL. A few normal indications of hypoglycemia include:

  • Unsteadiness
  • Quicker pulse
  • Perspiring
  • Hunger
  • Uneasiness
  • Drowsiness
  • Feeling feeble
  • Shivering

Check your blood glucose immediately if you experience any of these side effects. Adhere to your medical care supplier’s guidelines to treat hypoglycemia, (for example, the “15-15 Rule”) and inform them quickly.


What is dulaglutide used for?

An injectable medication for diabetes patients. It is necessary to use dulaglutide with a healthy eating and exercise routine for maximum benefits. It controls blood sugar levels in patients with type 2 diabetes ( a state in which the body is unable to regulate blood sugar levels ).

Can I use trulicity with insulin?

Yes, you can use them together. You just need to reduce the quantity of insulin. Trulicity and insulin jointly increase the regulation of blood sugar levels. Hence, more glucose is converted into energy. But only people with type 2 diabetes can use trulicity.

Does dulaglutide cause weight loss?

Although it is not a weight loss medication specifically, it just suppresses your appetite. A person taking trulicity can lose an average of 3-4 pounds. However, some people have experienced 15-30% weight gain.

Can non-diabetic patients take trulicity for weight loss?

People who don’t have diabetes should not take trulicity just for the sake of weight loss. Weight loss by trulicity is a concept that depends on your overall metabolic rate and food intake.

What foods should you avoid while taking Trulicity?

Avoid eating fatty foods and high-sugar foods. They slow your metabolic rate and are difficult to digest. Most commonly, these foods cause nausea when taken along with trulicity.

Bottom line

Trulicity is a GLP-1 agonist that treats Type 2 diabetes when used with diet and exercise. It is also helpful in treating heart problems in people with Type 2 diabetes, existing coronary disease, or risk factors for coronary disease.

While Trulicity isn’t FDA endorsed for weight loss, it helps in assisting individuals with shedding pounds, particularly at a portion of 4.5 mg each week. The most widely recognized incidental effects include stomach upset, similar to sickness, and heaving.

Individuals without Type 2 diabetes should not use Trulicity. Other GLP-1 agonists like Wegovy and Saxenda are FDA-supported for weight reduction at times. Converse with your medical services supplier if you’re keen on using a GLP-1 agonist for weight loss.

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